Ruthenium-based chemotherapeutics: are they ready for prime time?
نویسندگان
چکیده
منابع مشابه
Ready for Prime Time
Opening of the voltage-dependent Ca 2 channels permits influx of Ca across the plasma membrane, triggering diverse physiological processes. These channels are widely distributed in the cardiovascular system, constituting the main route for Ca entry essential for excitation and contraction. Ten unique 1 subunits, grouped in 3 families (CaV1, CaV2, and CaV3), that encode the low-voltage– activate...
متن کاملAirway pressure release and biphasic intermittent positive airway pressure ventilation: are they ready for prime time?
Airway pressure release ventilation and biphasic positive airway pressure ventilation are being used increasingly as alternative strategies to conventional assist control ventilation for patients with acute respiratory distress syndrome (ARDS) and acute lung injury. By permitting spontaneous breathing throughout the ventilatory cycle, these modes offer several advantages over conventional strat...
متن کاملReady for the Prime Time?
Metabolomics is one of the most rapidly growing areas of contemporary science. Although classic genetics aims to link variations in the DNA sequence directly to distinct phenotypes, “-omic” technologies allow us to shift the focus from the specific gene to the actual effects of the gene itself. Because neither the transcriptional or protein profile can be directly correlated with metabolite con...
متن کاملPharmacogenomics--ready for prime time?
Pharmacogenomics is receiving a great deal of attention in scientific circles and, increasingly, in the popular press because of the promise of personalized medicine. Short of being able to cure an illness or to prevent one, every clinician’s dream is to offer patients a precisely targeted drug at a precisely calibrated dose to address a specific ailment — and to do so without wreaking havoc on...
متن کاملCancer Biomarkers: Are We Ready for the Prime Time?
A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. In cancer, a biomarker refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker might be either a molecule secreted by a tumor or it can be a specific...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Chemotherapy and Pharmacology
سال: 2010
ISSN: 0344-5704,1432-0843
DOI: 10.1007/s00280-010-1293-1